Clear Understanding of Customer Pain Points
Ability to address complex customer issues for our biotech, animal health, biosimilars, academic and diagnostic clients. Successful examples of troubleshooting for issues such as low titers, complex glycosylation profiles, species-specific challenges, variability, process optimization, legacy platforms and more.
Established solution provider with 3-decades of successful track record. Efficient cell line development is critical in bringing biologics to market and requires a team of experienced scientists, a portfolio of well validated cell line platforms, and state of the art facilities. Aragen Bioscience delivers this combination and has completed more than 200 cell line development projects, with over 100 of those cell lines in the clinic following an investigational new drug (IND) application. More than four of Aragen Bioscience’s cell lines are producing marketed products.
Aragen Bioscience scientists are adept at working with a wide range of host cell lines (CHO, HEK, SP2/0, and NS0) and expression vectors and have successful case studies with a variety of molecular formats including IgG, IgM, Bispecific antibodies, Antibody fragments, Fc fusion proteins, Biosimilars, Enzymes, Recombinant proteins, and nimal biologics including feline, canine, murine, porcine antibodies.
6 CLD suites, 2 USP suites, 1 dedicated microbial suite, molecular biology and DSP suites and analytical labs, AMBR®250 multi-parallel bioreactor, 50L and 250L Single Use Bioreactors (SUB), GMP manufacturing capability.
Newly renovated 28,000 Sq. ft. ultramodern biologics facility in Morgan Hill, California (~30 minutes from San Jose, CA).
Experts with successful track records at Pfizer, Novartis, Zymergen, Syngene, Roche, GenScript and other companies serve on the Aragen Bioscience team. Together, they bring a wealth of knowledge, experience, and innovation to drive forward transformative solutions for clients.
Speed and Quality Promise
Rapid program initiation using open PO approach, Customized project dashboard to track all projects by status, stages, milestone delivery and timely delivery and regular project review calls.