Asthma is a common disease of the lungs. It is estimated that more than 22 million Americans have asthma, and it is one of the most common chronic diseases of childhood. Aragen’s state of the art analysis tools include:
Whole Body Plethysmograph (WBP)
- Airway hyper responsiveness,
- Respiratory rate
FlexiVent Lung Functional Analysis
- Blood glass measurement to monitor Hypoxia -related symptoms
PAS (periodic-acid-Schiff) Staining
- Detection of structures that contain high concentrations of carbohydrate macromolecules (eg. glycogen, glycoprotein, proteoglycan) typically found in mucus.
Serum and Bronchoalveolar Lavage Fluid Analysis
- Antigen-specific IgE and IgA levels
- Cytokines levels
Our rodent asthma models include induction by ova or other allergens (cedar pollen, dust mote antigen). Models can range from mild- to severe disease in order to evaluate a range of treatment options.