Press Releases

2020

Serum Institute and Aragen Bioscience Announce Collaboration on Vaccine Development

HYDERABAD, India & SAN JOSE, Calif.–(BUSINESS WIRE)– Aragen Bioscience, Inc, a subsidiary unit of GVK BIO and one of the leading pre-clinical CRO specializing in monoclonal antibody and other large-molecule product development and Serum Institute of India Pvt. Ltd. (Serum), the world’s largest vaccine manufacturer, are pleased to announce a collaboration for the development of multiple stable cell lines to support Serum’s HIV program. This partnership between Serum and Aragen unites two organizations that are committed to ‘Accelerating Life Sciences R&D’ with the goal of developing affordable monoclonal antibodies that improve the quality of human life.

Aragen will leverage its expertise with their RapTr platform utilizing proprietary vectors and CHO DG44 host cells to develop the cell lines. Combined with the analytics platform, Aragen is set to provide Serum with high expressing cell lines enabling Serum to quickly move their program forward into Manufacturing. With a proven track record of more than 50 years in developing affordable medicines, Serum will focus its efforts on advancing these novel molecules into impactful vaccines or therapies that treat and prevent diseases world-wide.

“We are delighted to partner with the global leader in Vaccines,” said Manni Kantipudi, Chairman, Aragen, & Chief Executive Officer, GVK BIO. “The Aragen team is recognized globally for its ability to clone and express challenging proteins. Through this collaboration with Serum, we expect to build on this expertise to develop and deliver affordable biologicals.”

“SIIPL is very pleased to join hands with Aragen. SIIPL is already in collaboration with IAVI and Scripps Research for discovery of novel monoclonal antibodies against HIV. With our manufacturing capabilities and this collaboration with Aragen to develop stable cell lines, SIIPL will be able to provide cost effective monoclonal antibodies against HIV for the developing and developed world,” stated Mr. Adar Poonawalla, CEO, SIIPL.

About GVK BIO

GVK BIO, a leading Contract Research & Development Organization servicing the global Life-sciences industry, is headquartered in Hyderabad, India with operations in five sites including Aragen Bioscience, Inc. in California, USA. Established in 2001, GVK BIO has over 19 years of experience across the Research and Development value chain with a focus on speed and quality while ensuring safety and compliance. GVK BIO’s team of over 2500 highly qualified scientists, backed by a no-conflict business model, well-defined and scalable processes, modern facilities, and a strong customer-centric partnering approach, focus on bringing its customers’ products to market. www.gvkbio.com

About Serum

Serum Institute of India Pvt. Ltd. was founded in 1966 by Dr. Cyrus Poonawalla with a mission of manufacturing life-saving immuno-biologics. Serum is the world’s largest vaccine manufacturer by number of doses produced and sold globally (more than 1.3 billion doses). It is estimated that about 65% of the children in the world receive at least one vaccine manufactured by Serum Institute. Vaccines manufactured by Serum are accredited by the World Health Organization, Geneva and are being used in approximately 170 countries across the globe.

Serum is ranked as India’s No. 1 biotechnology company, manufacturing highly specialized lifesaving biologics like vaccines using cutting edge genetic and cell-based technologies, antisera and other medical specialties.

The philanthropic philosophy of Serum continues with its work on newer vaccines and biologicals.

Learn more about Serum Institute of India at https://www.seruminstitute.com/

2019

GVK BIO announces the appointment of Axel Schleyer, Ph.D. as Chief Executive Officer, Aragen Bioscience, Inc.

May 08, 2019, Hyderabad, India/California, US: GVK BIO is pleased to announce the appointment of  Dr. Axel Schleyer as Chief Executive Officer, Aragen Bioscience Inc.  Aragen, a wholly-owned subsidiary of GVK BIO, is a leading Contract Research Organization focused on accelerating biologicals product development with an integrated offering that includes antibody discovery and humanization, stable cell line development, recombinant protein production and purification, and differentiated diseases models.

“I am delighted to welcome Dr. Axel Schleyer as the Chief Executive Officer, Aragen Bioscience. Axel brings a wealth of business, technology, regulatory and strategic acumen, and has an impressive record of consistently delivering high performance with a customer focus, said Manni Kantipudi, Chairman, Aragen Bioscience, Director & CEO, GVK BIO. “We are confident that under his leadership, Aragen will expand its offering, and build on its growth over the past few years”.

“I am excited to lead Aragen Bioscience and look forward to assisting our customers in developing solutions that impact human health. With large molecules contributing to approximately 40% of the global portfolio, interest in Biologics research continues to grow rapidly” added Dr. Axel Schleyer. “With its strong scientific leadership, ‘customer first’ culture, state-of-the-art infrastructure, and an ideal location in the Bay area, Aragen is well positioned to benefit from market trends.

A seasoned Pharmaceutical and Biotechnology professional, Dr. Schleyer has over two decades of industry experience, building and leading high-performance teams, spearheading global business initiatives, and formulating business strategies resulting in successful outcomes. Prior to joining Aragen, Dr. Schleyer served as Senior Vice President, AGC Biologics and has held roles of increasing responsibilities at Lonza, Siegfried, Baxter Healthcare and Boehringer Ingelheim.

Dr. Schleyer has completed his postdoctoral studies at The Scripps Research Institute, La Jolla, CA and at Carlsberg Institute, Copenhagen, Denmark. He completed his Ph.D. in Chemistry from the University of Hamburg, and holds a Master of Business Administration degree from California State University, San Marcos.

About GVK BIO

GVK BIO, a leading Contract Research & Development Organization servicing the global Biopharma industry; is headquartered in Hyderabad, India with operations in five sites including California, USA. Established in 2001, GVK BIO has over 18 years of experience across the Research and Development value chain with a focus on speed and quality while ensuring safety and compliance. GVK BIO’s team of over 2100 highly qualified scientists, backed by a no-conflict business model, well-defined and scalable processes, modern facilities, and a strong customer-centric partnering approach, focus on bringing its customers’ products to market. www.gvkbio.com

About Aragen Bioscience, Inc.

Aragen Bioscience, Inc., a wholly owned subsidiary of GVK BIO, is a leading contract research organization based in the San Francisco Bay Area. Aragen Bioscience offers a diverse set of    In Vitro and In Vivo services for the discovery, characterization, activity assessment and early development of biologic and diagnostic products. www.aragenbio.com

Contact

sarat.patanaik@gvkbio.com

2018

Aragen Bioscience Expands RapTr Cell Line Development Services

San Francisco, CA  March 19, 2018 – Aragen Bioscience, Inc, a leading pre-clinical CRO specializing in monoclonal antibody and other large-molecule product development, announced today that their RapTr™ Cell Line Development Services have been expanded to include CHO-GS cell lines. The company is introducing their new services at the Bioprocess International West Conference in San Francisco this week.

RapTr™ services combine proven host cell lines and vector combinations with an innovative clone selection process. This results in a highly flexible and customizable platform that rapidly delivers high titers, allowing researchers to characterize and evaluate product quality at all stages of development — from early-stage discovery to manufacturing. Both RapTr cell lines are regulatory-friendly and royalty-free.

“We’re excited to broaden our RapTr™ services to include the CHO-GS cell line. This expansion will give our clients much more flexibility with development decisions”, said Virginie Menard Rose, Ph.D., Director of Cell Line Development and Upstream Process Development. “Our royalty-free, fee-for-service approach also eliminates the requirement for negotiating a third-party cell licensing agreement.

About Aragen Bioscience, Inc.

Aragen Bioscience, Inc., a wholly owned subsidiary of GVK BIO, is a leading contract research organization based in the San Francisco Bay Area. Aragen Bioscience offers a diverse set of In Vitro and In Vivo services for the discovery, characterization, activity assessment and early development of biologic and diagnostic products.

2017

Aragen Bioscience Announces AAALAC Accreditation

MORGAN HILL, CA November 10, 2017  – Aragen Bioscience announced today full accreditation from the AAALAC (Association for Assessment and Accreditation of Laboratory Animal Care). “Animal research continues to play an important role in the development of novel and improved medicines to treat human diseases. We acknowledge that animal research is a subject of ethical concern for both our partners and the public; we take our responsibility to animal welfare very seriously,” commented Malavika Ghosh, Vice President, Preclinical Research. “We also recognize that laboratory animal research has proven to be an essential element in the development of therapeutics. As part of our commitment to the ethical and responsible treatment of animals in research, we have applied for and received full accreditation from AAALAC.” AAALAC accreditation is a voluntary, peer-reviewed assessment by a private nonprofit organization that promotes the humane treatment of animals in science. AAALAC accreditation is recognized worldwide as the “gold standard” for animal research programs.

“Our partners have come to rely on us for both the design and implementation of their preclinical studies “ Dr. Ghosh continued. “AAALAC accreditation helps demonstrate that we are engaged in responsible animal research and dedicated to good science.”

About Aragen Bioscience, Inc.

Aragen Bioscience, Inc., a wholly-owned subsidiary of GVK BIO, is a leading contract research organization based in the San Francisco Bay Area. Aragen Bioscience offers a diverse set of In Vitro and In Vivo services for the discovery, characterization, activity assessment and early development of biologic and diagnostic products

RapTr Cell Line Development services introduced

SAN DIEGO, CA June 20, 2017 – Aragen Bioscience, Inc, a leading pre-clinical contract research organization specializing in the discovery and preclinical development of high-value biotech and pharmaceutical products, announced today at the BIO International Convention the introduction of RapTr™ services. RapTr™ Cell Line Development Services combine the proven CHO-DG44 host cell line and vector combination with an innovative clone selection process. The results are a highly flexible and customizable platform delivering high titers in a rapid timeframe from early stage Discovery through to the Clinic. RapTr also incorporates state-of-the-art analytical methods to characterize and evaluate product quality at all stages.  As RapTr is based on CHO-DG44, it is regulatory-friendly and royalty-free.

“Building on our decades of experience in cell line development and recent investments in expanding our biologics team and facilities, we’re excited to announce RapTr™. We believe that our suite protein expression and analytical services will give our clients tremendous flexibility in developing cell lines and generating high quality proteins using a single scalable platform regardless of their stage of development.” said Oren Beske, Ph.D., President of Aragen Bioscience.

About Aragen Bioscience, Inc.

Aragen Bioscience, Inc., a wholly-owned subsidiary of GVK BIO, is a leading contract research organization based in the San Francisco Bay Area. Aragen Bioscience offers a diverse set of In Vitro and In Vivo services for the discovery, characterization, activity assessment and early development of biologic and diagnostic products

2016

July 11, 2016
MORGAN HILL, California – July 11, 2016: Aragen Bioscience, Inc. (Aragen), leading pre-clinical contract research organization specializing in the discovery and early development of high-value biologics and diagnostic products has appointed Oren Beske, Ph.D. as the President of Aragen Bioscience.

January 26, 2016
MORGAN HILL, California – January 28, 2016: Aragen Bioscience, Inc. (Aragen), leading contract research organization specializing in the study and early development of biologic and diagnostic products, has initiated construction on a new, state of the art research facility.

2015

September 8, 2015
Aragen Bioscience Announces Licensing Agreement for Protein Production Technology from ProteoNic Biotechnology


2014

January 2, 2014
GVK BIO and Aragen Bioscience Sign Definitive Agreement to Acquire Aragen Bioscience, Inc.


2013

May 2, 2013
Aragen Bioscience and Innovent Biologics Announce Collaboration for Biotherapeutic Product Development

September 12, 2013
Bullet Bio Provides Update On Recent Financing And Results From Proof-Of-Concept Study For Lead Product Candidate


2012

August 2, 2012
Aragen Bioscience, Inc. successfully completes antibody humanization project


2011

October 26, 2011
XOMA and Aragen Bioscience Announce Antibody Humanization Services AgreementXOMA and Aragen Bioscience Announce Antibody Humanization Services Agreement

June 1, 2011
Aragen Bioscience Announces Cooperative Research and Development Agreement with the U.S. Army

April 5, 2011
Aragen Bioscience Awarded Three PreClinical Development NIAID Subcontracts