Protein Analytics
Aragen Bioscience, a leading CRO, offers a range of analytical methods utilizing multiple assay platforms that be used to characterize a broad range of proteins expressed and purified by various methods:
- Protein activity
- Binding affinity (FortéBio Octet® RED96 System)
- Enzyme activity
- Cell-based assays
- In vivo testing
- Aggregation status
- SDS-PAGE
- SEC-HPLC
- Optical density
- Protein stability (Unchained Labs Uncle)
- Tm & Tagg
- ΔG
- Isothermal stability
- Thermal recovery
- Sizing & polydispersity
- Sizing with thermal ramp
- B22 & kD
- Viscosity
- Protein integrity and structure
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- SEC-HPLC
- SDS-PAGE
- N-glycan analysis
- Western Blot
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- Protein mass (Agilent HPLC-CHIP/QTOF)
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- Accurate mass: proteins, protein-drug conjugates
- Peptide and Glycan mapping
- Determination of post-translations modifications either in known or unknown samples.
- Standard COAs
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Our team will work closely with you from concept through delivery. Together, we’ll develop a set of project deliverables tailored to your specifications of scale, purity, activity and other analytical characteristics on a timeline that meets your needs. The protein science group works in close collaboration with Aragen’s cell biology and in vivo teams to provide a tightly integrated solution for your development needs.
Ready to take the next step?