Careers

Director/Sr. Director – Potency & Protein Analytical Sciences

Our protein analytical sciences group supports discovery projects. Going forward we are strengthening this group as a separate Business Unit (BU) and expanding the scope to provide services for characterization of biological products, which includes the determination of physicochemical properties, biological activity, immunochemical properties, purity and impurities in accordance with the requirements of the ICH Q6B Guidance.

This role is responsible for running the BU which includes capability building, scientific delivery of the projects, help S&M for customer acquisition and retention, Profit & Loss of the BU. This position will be reporting to the President Aragen.

Responsibilities –

Strategic Development: 

  • Develop strategies and ensure execution for the Business Unit which are aligned with the short, medium and long term goals of the company
  • Unique services proposition to clients and partners and develop long term partnerships.
  • Partner with other BU heads & S&M, identify new services & markets and ensure the BU is prepared to meet customer expectations.

Operational Efficiencies: 

  • Provide direction to the team in driving operational efficiencies, cost management and enhancing productivity.
  • Build/Develop process, systems and metrics that drive performance and productivity and ensure business is competitive to the external competition.
  • Envisions and establishes capabilities including differentiating capabilities
  • Ownership and accountability of the scientific quality of the BU, proactively enables the timely execution of projects, Customer interaction and communication
  • Supporting other BUs for their bioanalytical needs

People & Organization Development: 

  • Create an environment to nurture teamwork and synergy.
  • Build infrastructure and people capacity for achieving the growth targets set for the company

Financial Performance

  • Ensure financial performance of the BU as per the targets

Compliances 

  • Develop and comply the regulatory guidelines
  • Drive the culture of compliance to the local laws and corporate guidelines

Required Educational Qualification and experience

  • PhD with  12+ yrs. of relevant experience in Biological Solutions industry
  • Understanding of Biologics/ Biosimilars markets, experience in running P&L, hiring and development of scientific talent

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Accountant

We are seeking a motivated professional with experience in small to mid-sized service organization who can combine their analytical skills and thorough knowledge of accounting principles.  In this role the Accountant will have responsibility of end to end accounts payable & accounts receivable, customer invoicing, month end closing and capitalization of fixed assets.  This role will work closely with project management staff to ensure invoices are processed timely and ensure timely follow up on overdue items.  Additional duties include payroll, tax, compliance requirements and other duties as assigned.     

Requirements for the position include: 

  • Education: B.S. degree in Accounting with 3+ years of experience.  
  • Proficient in MS Office (Word, & Power point) & Advanced Excel 
  • Working experience in QuickBooks software
  • Experience with general ledger functions and the month-end/year-end close process
  • Working knowledge of Generally Accepted Accounting Principles (GAAP)
  • Excellent communication skills and the ability to work well as a member of a team is required.
  • Accuracy and strong attention to detail 

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Scientist

We are seeking a motivated professional to join the Protein Sciences Division supporting protein analytics for protein bioproduction, process development, hybridoma antibody discovery and cell line development. Experiments will include protein formulation and stability studies, support of hybridoma campaigns with off rate ranking, binning, and epitope mapping.  Experience in protein and antibody ligand and enzyme kinetics is essential.

Requirements for the position include:

  • Education: A Ph.D in Biology or Biochemistry and at least 1-3 years of post-graduate experience in a professional environment. Intuitive knowledge and technical excellence in protein kinetics and biophysical characterization of proteins.
  • Ability to drive strategies and problem solve for biochemical and biophysical characterization of a diverse range of proteins from many different customers.
  • Good communication skills and the ability to work well as a member of a team is required.Excellent oral and written communication skills
  • Proficiency in Word, Excel, PowerPoint and data analysis are expected
  • Experience in enzymology (chromogenic/fluorogenic assays), Ligand binding kinetics (ForteBio/Biacore),
  • Formulation and stability assays with experience in DSC, DSF/UNCLE™, SLS and DLS, ELISA and western blot analysis including assay qualification,
  • Mass Spectrometry and SEC-MALs (optional),
  • Cell based potency assays including the AlphaLISA format (optional).

WORKING CONDITIONS:

  • Laboratory setting
  • Able to lift up to 30 lbs.
  • Based on project needs working schedule may include some after-hours or weekend duties

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Scientist/Senior Research Associate/Research Associate

We are seeking a Scientist or experienced Research Associate who under the direction of a senior scientist or director, the successful candidate will be responsible for the execution of all technical tasks and data analysis associated with preclinical research projects.  In addition, depending on the position, it will be necessary to manage research associates who are executing preclinical assay projects for clients. The candidate will be an innovative, independent and motivated professional. He or she will have significant and broad experience in combinations of the following areas:  maintenance of cell cultures, inventory of samples originating from the preclinical projects, cell based assays, ELISA. The candidate will be able to perform analytical assays used using ELISA, Western Blot and related techniques. The candidate will have experience with troubleshooting assays and should be capable of data analysis, data presentation and interested in learning new areas of research.

Requirements for the position include:

  • BS, MS, Ph.D. in any discipline of Biology or chemical engineering
  • Experience in cell culture within a drug discovery organization or a CRO
  • Deep knowledge of functional analysis using different analytical techniques
  • Working in an environment of team work and collaboration
  • Excellent communication and interpersonal skills and proven success working in matrix environments

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Animal Research Technician (Part Time)

We are currently seeking an experienced animal technician for our in vivo research projects. He/She will perform duties involving the daily care of research animals for experimental purposes, which includes daily health monitoring (taking body weight measurement), collecting other in vivo data (e.g., tumor measurement), dosing of animals (ip, iv, sc, and po), and collecting the organ samples (bleeding i.e., tail or retro-orbital bleeding, or cardiac bleeding and extracting organ tissues). All work will involve the direct handling of laboratory mice with a potential work with rats and other rodents. The candidate is also required to work in a barrier facility and wearing proper PPE. Interested candidates should have several years of pertinent experience in a small to medium scale animal care facility and meet the following requirements:

  • High school degree or equivalent, college degree preferred.
  • Hands-on experience with handling laboratory rodents.
  • Proficient with compound dosing and collection of samples for PK/PD
  • Competent at entering data onto a laptop computer.
  • Skill and knowledge to apply principles of sanitizing and disinfecting cages 
in compliance with AAALAC standards.
  • Availability to work variable schedule including weekends and holidays.
  • Experience in surgical techniques and/or in vivo disease models is highly
  • AALAS certification (ALAT or higher) preferred.
  • Accurate record keeping and troubleshooting skills
  • Self-motivated, flexible, and willing to meet strict time lines
  • Strong interpersonal communication skills
  • Ability to work in a fast paced, goal oriented, team-based environment 
Aragen is an equal opportunity employer. We offer a challenging work environment with excellent salary and benefits.

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Research Associate/Senior Research Associate

Protein Purification and Analytics

We are seeking a motivated professional with experience in the purification and characterization of recombinant proteins. A strong working knowledge of downstream process development and final product characterization is required. A broad knowledge of protein chemistry and enzymology is desired. The successful candidate will demonstrate the ability to diligently and expertly handle multiple projects and tasks simultaneously and generate accurate documentation.

Requirements for the position include:

  • BS or MS in biochemistry or related field or comparable experience.
  • At least five years of relevant industry experience.
  • Has routinely performed SDS-PAGE, IEF-PAGE, Native-PAGE, Western Blot, colorimetric protein quantitation assays, ELISA, chromogenic activity assays and UV spectrophotometry.
  • Hands-on experience on the use of diverse chromatographic resins, on column packing, on ultrafiltraion and diafiltration (UF/DF), on cell culture harvest clarification and on sterile techniques.
  • Program, operate, maintain and troubleshoot equipment such as AKTA purification systems such as Purifier and Pure, AKTA flux cross flow filtration system and Agilent 1100 HPLC.
  • Familiarity on operating capillary electrophoresis and mass spec equipment a plus.
  • Good oral and written communication skills.
  • Able to maintain detailed written records.
  • Ability to work independently as a member of a matrixed team in a fast paced laboratory environment.
  • Managerial experience and familiarity with cGMPs are highly desired.

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Scientist; Cell Line Development

We are seeking a Scientist who under the direction of a senior scientist or director will be responsible for the execution of all technical tasks and data analysis associated with cell line development projects.  In addition, the position will be necessary to manage research associates who are executing cell line development and process development projects for clients. The candidate will be an innovative, independent and motivated professional. He or she will have significant and broad experience in combinations of the following areas:  stable and transient expression of proteins and antibodies, development of recombinant cell lines, early-stage upstream process development and production of proteins and monoclonal antibodies in shake flasks and bench-scale bioreactors. The candidate will be able to perform analytical assays used to characterize expressed proteins and antibodies including ELISA, Western Blot, BLI measurement. The candidate will have experience with troubleshooting protein expression, cell culture and assay related problems.

POSITION DUTIES AND RESPONSIBILTIES:

  • Experience in enzymology (Chromogenic/Fuorogenic assays),
  • Ligand binding kinetics (ForteBio/Biacore),
  • Formulation and stability assays with experience in DSC, DSF/UNCLE™, SLS and DLS,
  • ELISA and western blot analysis including assay qualification,
  • Mass Spectrometry and SEC-MALs (optional),
  • Cell based potency assays including the AlphaLISA format (optional).

REQUIREMENTS:

  • BS, MS, Ph.D. in any discipline of Biology or chemical engineering
  • Experience in mammalian cell line development within a drug discovery organization or a CRO
  • Deep knowledge of mammalian cell protein expression and upstream process development across different platforms.
  • Deep and current knowledge of bioreactor design, function and maintenance. Direct involvement in a GMP process or transfer to a GMP facility.
  • Excellent communication and interpersonal skills and proven success working in matrix environments

Apply Now

Aragen Bioscience provides a challenging work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. The Company is located in Morgan Hill, California, at the south end of the Silicon Valley. We offer excellent salary and benefits. Aragen is an equal opportunity employer.