Careers

Senior Scientist / Principal Research Scientist – Purification – Morgan Hill

Aragen’s Bioproduction group is seeking an experienced protein purification Senior or Principal Research Scientist to join a high-functioning team responsible for delivering R&D and GLP protein reagents for our clients. You will have opportunities to take ownership of a wide-ranging set of projects from purification design to process development and tech transfer and for a variety of protein types and therapeutics. As part of a rapidly growing team, you will be able to make decisions and influence changes as we grow the organization and expand capabilities to meet clients’ goals and ultimately improve patient outcomes.

The incumbent will split time between communicating with and understanding clients’ projects and designing and executing lab experiments. Effective internal and external communication and collaboration skills are essential for success in this position. The ideal candidate will maintain a high-level of awareness of recent developments in separation sciences and protein analytical techniques.

Experience and Qualifications

  • PhD with 5+ years or BS/MS with 10+ years of hands-on experience designing, executing, and troubleshooting bench- and/or pilot-scale protein purification.
  • In-depth understanding of protein chemistry and industry-standard purification processes (affinity, IEX, SEC, viral inactivation and filtration, depth filtration, TFF, UFDF, etc.), equipment (AKTA), and software (UNICORN, Osi Pi Historian).
  • Creative thinker that can identify method improvements to address issues and gaps
  • Demonstrate ability to work independently and on cross-functional teams
  • Strong attention to detail
  • People and project management experience is a plus

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Sr. Animal Research Associate/Technician – Morgan Hill, CA

Aragen Bioscience offers molecular, cell biology, and immunology services to the biotech industries locally, nationally, as well as internationally. Aragen’s offices are located in Morgan Hill, California, at the south end of the Silicon Valley. Great reverse Commute!

We are currently seeking an experienced animal technician for our in vivo research projects. Animal technician will perform duties involving the daily care of research animals for experimental purposes, which includes daily health monitoring (taking body weight measurement), collecting other in vivo data (e.g., tumor measurement), dosing of animals (ip, iv, sc, and po), and collecting the organ samples (bleeding i.e., tail or retro-orbital bleeding, or cardiac bleeding and extracting organ tissues). All work will involve the direct handling of laboratory mice with a potential work with rats and other rodents. The candidate is also required to work in a barrier facility and wearing proper PPE.

Interested candidates should have several years of pertinent experience in a small to medium scale animal care facility and meet the following requirements:

  • High school degree or equivalent, college degree preferred.
  • Hands-on experience with handling laboratory rodents.
  • Proficient with compound dosing and collection of samples for PK/PD
  • Competent at entering data onto a laptop computer.
  • Skill and knowledge to apply principles of sanitizing and disinfecting cages in compliance with AAALAC standards.
  • Availability to work variable schedule including weekends and holidays.
  • Experience in surgical techniques and/or in vivo disease models is highly
  • AALAS certification (ALAT or higher) preferred.
  • Accurate record keeping and troubleshooting skills
  • Self-motivated, flexible, and willing to meet strict time lines
  • Strong interpersonal communication skills
  • Ability to work in a fast paced, goal oriented, team-based environment

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Senior Research Associate/Scientist – Purification – Morgan Hill, CA

Aragen’s research reagent group is seeking a Senior Research Associate or Scientist with extensive experience in protein purification and characterization. The purification team is responsible for delivery high-quality R&D protein reagents for our clients. Demonstrated expertise in protein purification method development, column chromatography methods, such as affinity, SEC, IEX, and HIC, and viral inactivation/filtration, depth filtration, TFF and UFDF operation is required, ideally utilizing Akta FPLC systems. Other expertise will be considered, but the ability to develop and implement purification projects of technically complex natures based on client’s objectives is essential.

Responsibilities will include designing and executing lab experiments, coordinating experiments across functional groups, and accurately analyzing and documenting data. Effective internal and external communication and collaboration skills are essential for success in this position. The ideal candidate will maintain a high-level of awareness of recent developments and background in separation sciences and protein analytical techniques.

Requirements
  • BS, MS or PhD in life sciences or chemical engineering with 5 + years (BS, MS) or 2+ years (PhD) of industrial experience in protein purification.
  • Familiarity of Process Development (including chromatography, depth and membrane filtration and ultrafiltration.)
  • Working knowledge of Unicorn Software and hands on experience using AKTA systems.
  • Independently operate analytical equipment such as analytical HPLC, plate readers,
  • Excellent written and oral communication skills
  • Ability to work in a fast-paced environment and manage multiple projects/tasks. Ability to supervise and manage the activities of other staff is a plus.
  • Ability to rapidly make decisions based on data, knowledge and sound judgement

Aragen Bioscience provides a stimulating work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. The Company is in Morgan Hill, California, at the south end of the Silicon Valley. We offer excellent salary and benefits. Aragen is an equal opportunity employer. No Sponsorship available.

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Scientist/Research Associate – Morgan Hill, CA

We are seeking a Scientist or experienced Research Associate who under the direction of a senior scientist or director, the successful candidate will be responsible for the execution of all technical tasks and data analysis associated with preclinical research projects. In addition, depending on the position, it will be necessary to manage research associates who are executing preclinical assay projects for clients. The candidate will be an innovative, independent and motivated professional. He or she will have significant and broad experience in combinations of the following areas: maintenance of cell cultures, inventory of samples originating from the preclinical projects, cell based assays, ELISA. The candidate will be able to perform analytical assays used using ELISA, Western Blot and related techniques. The candidate will have experience with troubleshooting assays and should be capable of data analysis, data presentation and interested in learning new areas of research.

Requirements

  • BS, MS, PhD in any discipline of Biology or chemical engineering
  • 4 + years experience in cell culture within a drug discovery organization or a CRO
  • Deep knowledge of functional analysis using different analytical techniques
  • Working in an environment of team work and collaboration
  • Excellent communication and interpersonal skills and proven success working in matrix environments

Excellent communication and interpersonal skills and proven success working in matrix environments

Aragen Bioscience provides a challenging work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. The Company is located in Morgan Hill, California, at the south end of the Silicon Valley. We offer excellent salary and benefits. Aragen is an equal opportunity employer.

Apply Now

Head of CCM – Morgan Hill, CA

Technical

  • Provide overall leadership to Aragen’s Cell Culture Manufacturing (CCM) operations, develop, implement and oversee group objectives, ensuring alignment with site goals.
  • Responsible for product transfer, process validation, and process improvement.
  • Responsible for all aspects of clinical manufacturing in the following areas: Cell Expansion, Cell Culture, Purification, Solution Preparation and Weigh/Dispense. Employee will lead and work seamlessly across all areas and will be a Subject Matter Expert (SME) for multiple areas.
  • Strong partnership with Quality to support manufacturing operations and to support Quality and Compliance at all times.
  • Ensure systems and staff are prepared for inspections by regulatory authorities and customer audits.
  • Specify processing requirements in support of product and quality related topics.
  • Monitors and controls all aspects of manufacturing processes using data trending and /or statistical process control.
  • Works cross functionally to ensure process is controlled and issues are escalated and investigated.
  • Analyze process and facility capabilities to identify opportunities for improvement.
  • Lead the transfer of products/processes from and to Aragen CCM.
  • Provide technical support to the front-line operations support groups in the Manufacturing Department to troubleshoot and improve process operations.
  • Design and execute laboratory experiments targeted at improving process robustness.

Leadership & People Management

  • Develop Aragen’s CCM group to meet goals in staff development, group effectiveness, efficiency, process improvement, customer service, and safety.
  • Establish culture of strong team spirit, effective communications, sense of urgency, high motivation and inspire team to achieve short and long-term goals.
  • Manage groups organizational growth and development including hiring, promotion, and compensation and provide training of personnel on company’s and department policies systems and processes.
  • Demonstrates problem solving abilities and is change advocate.

Financial

  • Plan, develop and oversee CCM budget.

Education/Experience

  • Minimum of Master’s degree in the life sciences or in an engineering discipline (Ph.D. preferred).
  • At least 10 years of experience in the GMP cell culture manufacturing
  • At least 7 years of managerial experience

Knowledge/Skills/Competencies

  • In depth knowledge of Biopharmaceutical manufacturing processes and GMP requirements.
  • Excellent written and verbal communication skills.
  • Strong team leader with demonstrated ability to manage complex projects, lead technical teams, and support manufacturing operations in a flexible and dynamic team environment.
  • Experience in leading, motivating, developing, and sustaining creative output from a diverse technical staff.

Apply Now

Aragen Bioscience provides a challenging work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. The Company is located in Morgan Hill, California, at the south end of the Silicon Valley. We offer excellent salary and benefits. Aragen is an equal opportunity employer.