Molecular Biology

Aragen Bioscience scientists have many years of experience in the use of molecular biology techniques resulting in the cloning and constructing of novel genes for use in the generation of unique reagents and recombinant mammalian cells for biopharmaceutical production.

Our services include:

• Isolation of nucleic acids (genomic and plasmid DNA, RNA)
• RT-PCR detection methods and generation of cDNA
• Primer design
• Vector construction - constitutive and inducible expression vectors for mammalian, insect, bacterial and yeast systems
• Codon optimization for efficient expression in different hosts
• Chimeric antibody generation
• Humanization via CDR Grafting
• Antibody isotype switching
• Site specific mutagenesis